John Lithgow and Jimmy Smits will reprise their Dexter roles in Dexter: Resurrection.

Lithgow starred as serial killer Arthur Mitchell in the fourth season of Dexter and made a cameo in Dexter: New Blood. Smits played Miami Assistant District Attorney Miguel Prado in season three.

Michael C. Hall will reprise his role as serial killer Dexter Morgan alongside David Zayas as Angel Batista, Jack Alcott as Harrison Morgan, James Remar as Harry Morgan, and David Magidoff as Teddy Reed.

Peter Dinklage will play the season’s main villain, Leon Prater, a billionaire venture capitalist, with Uma Thurman as Charley, a former Special Ops officer who serves as his right-hand woman.

Krysten Ritter, Neil Patrick Harris, Eric Stonestreet, David Dastmalchian, and Steve Schirripa will guest star. Other newcomers to the franchise include Ntare Guma Mbaho Mwine, Kadia Saraf, Dominic Fumusaand, and Emilia Suárez.

Original Dexter showrunner Clyde Phillips returns while fellow Dexter alumnus Marcos Siega serves as producing director. He’ll helm four episodes, with Monica Raymund (“Dexter: Original Sin”) directing the other four.