A new trailer from Guillermo del Toro‘s Frankenstein has dropped.

The film follows brilliant but egotistical scientist Victor Frankenstein, who brings a creature to life in a monstrous experiment that ultimately leads to the undoing of both the creator and his tragic creation.

Oscar Isaac (Dune) stars in Del Toro’s movie as mad scientist Victor Frankenstein, Jacob Elordi (Saltburn) as Frankenstein’s monster, Mia Goth (MaXXXine) as Elizabeth Lavenza, and Christoph Waltz (Inglourious Basterds) as Dr. Pretorius.

Felix Kammerer (All Quiet on the Western Front), Lars Mikkelsen (“Ahsoka”), David Bradley (Harry Potter), Christian Convery (“Sweet Tooth”), Ralph Ineson (The Witch), and Charles Dance (“Game of Thrones”) round out the cast.

The adaptation of Mary Shelley‘s genre-defining 1818 novel opens in select theaters on October 17 before streaming on Netflix November 7.